1、 国家自然科学青年基金:香港巨牡蛎Fas 信号通路在诱导细胞凋亡和免疫防御中的功能研究,(No.31202021,2013-2015),24万,结题。
2、 广东省海洋渔业科技推广专项: 海洋生物抗菌肽制备的关键技术攻关,(A201301B08,2013-2015),30万,结题。
3、 国家自然科学面上基金:逆境胁迫下香港牡蛎DNA损伤与线粒体凋亡途径的活化机制, (No. 31572661,2016-2019),71.3万,结题。
4、 广州市自然科学基金:香港巨牡蛎凋亡标志性基因Caspase-3 的功能分析与应用,(No.201707010177,2017-2020),20万,结题。
5、 海南省自然科学基金:西沙砗磲人工繁育及放流,(No.202103021223,2021.1 -2022.12),70万,在研。
6、 广东省自然科学基金:TNFR27信号途径在溶珊瑚弧菌诱导牡蛎幼苗大规模死亡中的分子应答机制,广东省自然科学基金,10万,(No. 2114050000901, 2021.1 -2023.12);在研。
6. “南海重要岛礁及邻近海域生物资源评价与生态修复”子课题5“岛礁新型生态牧场的构建与示范”(2018YFC1406505)子课题。国家重点研发计划, 168万, 2018.8 -2021.8;在研。
发表论文
1. ChBax/Bak as key regulators of the mitochondrial apoptotic pathway: cloned and characterized in Crassostrea hongkongensis. Fish Shellfish Immunol 2015, 45:59-66.第一作者
2. Cloning, characterization and comparative analysis of four death receptor TNFRs from the oyster Crassostrea hongkongensis. Fish Shellfish Immunol 2016, 59:288-97.第一作者
3. Prostaglandin E receptor 4 (PTGER4) involved in host protection against immune challenge in oyster, Crassostrea hongkongensis.Fish Shellfish Immunol, 2015 42:225-32.共一
4. Identification and function of an evolutionarily conserved signaling intermediate in Toll pathways (ECSIT) from Crassostrea hongkongensis.Dev Comp Immunol2017, 311-319.共一
5. c-Jun N-terminal kinase (JNK) is involved in immune defense against bacterial infection in Crassostrea hongkongensis.Dev Comp Immunol2015,53(1):244-252.共通讯
6. ChAkt1 involvement in orchestrating the immune and heat shock responses in Crassostrea hongkongensis: Molecular cloning and functional characterization.Fish Shellfish Immunol2015, 47:1015-23.共通讯
7. Molecular cloning and expression analysis of an apoptosis-associated gene Daxx from zebrafish, Danio rerio.Fish Shellfish Immunol 2015, 45, 59-66.通讯
8. Molecular identification and functional characterization of a tumor necrosis factor (TNF) gene in Crassostrea hongkongensis. Immunobiology, 2016,32 1-9.共通讯
9. A novel p38 MAPK indentified from Crassostrea hongkongensis and its involvement in host response to immune challenges.Mol Immunol2016, 79:113-24.共通讯
10. A molluscan extracellular signal-regulated kinase is involved in host response to immune challenges in vivo and in vitro,Fish Shellfish Immunol2017,751-758.共通讯
11. Characterization and functional analysis of a Caspase 3 gene: Evidence that ChCas 3 participates in the regulation of apoptosis in C.hongkongensis. Fish Shellfish Immunol2020, 98:122-129.共通讯
12. Mechanistic molecular responses of the giant clam Tridacna crocea to Vibrio coralliilyticus challenge. PLoS One, 2020, 15(4):e0231399共通讯
发明授权专利
1. 一种血清淀粉样蛋白A及其编码基因和应用 ZL201410084163.2,授权,2015.12.2
2. 一种纤维胶凝蛋白及其编码基因和应用 ZL 201410137128.2 ,授权,2017.3.22
3. 一种牡蛎细胞凋亡基因SMAC基因及其在制备病理检测诊断试剂中的应用ZL 201810300697.2授权,2020.2.14