1. 软珊瑚共附生真菌抗植物病原菌肽类化合物的结构多样性挖掘及其初步作用机制,主持,国家自然科学基金面上项目, 2020.01.01-2023.12.31;
2. 以gp41为靶点南海海洋真菌二倍半萜类HIV进入抑制剂的筛,主持,国家自然科学基金应急管理项目, 2018.01-2018.12;
3. 三沙永兴岛两种短指软珊瑚中抑制NF-κB活性萜类化合物的发现,主持,国家基金青年基金项目, 2014.01-2016.12;
4. 两株海洋真菌产细胞松弛素类化合物的深入挖掘及其抗肿瘤活性研究,主持,广东省自然科学基金项目, 2018.05.01-2021.04.30;
5. 一株红树林底泥真菌Penicillium sp. SYFz-1产生物碱潜力挖掘及其NF-κB活性筛选,主持,广东省自然科学基金, 2014.10-2017.10;
6. 南海深海真菌抗结核活性先导化合物的筛选和挖掘,主持,广东省促进经济高质量发展专项资金海洋经济发展项目, 2019.04.01-2021.03.31;
7. 以gp41为靶点海洋真菌肽类HIV进入抑制剂的筛选和发现, 主持,广州市科技计划项目, 2018.04.01-2021.03.31
代表论文:
1. Bin Yang; Jieyi Long; Xiaoyan Pang; Xiuping Lin; Shengrong Liao; Junfeng Wang; Xuefeng Zhou; Yunqiu Li; Yonghong Liu, Structurally diverse polyketides and phenylspirodrimanes from the soft coral-associated fungus Stachybotrys chartarum SCSIO41201. Journal of Antibiotics, 2021, 74, 190-198.
2. Jixing Li; Huaming Tao; Xin-Xin Lei; Han Zhang; Xuefeng Zhou; Yonghong Liu; Yunqiu Li; Bin Yang, Arthriniumsteroids A-D, four new steroids from the soft coral-derived fungus Simplicillium lanosoniveum SCSIO41212. Steroids, 2021, 108831-108831.
3. Jie-Yi Long; Jun-Feng Wang; Sheng-Rong Liao; Xiu-Ping Lin; Xue-Feng Zhou; Yun-Qiu Li; Bin Yang; Yong-Hong Liu, Four new steroids from the marine soft coral-derived fungus Penicillium sp. SCSIO41201. Chinese journal of natural medicines, 2020, 18, 250-255.
4. Xiuping Lin; Wen Ai; Meng Li; Xuefeng Zhou; Shengrong Liao; Junfeng Wang; Juan Liu; Bin Yang; Yonghong Liu, Collacyclumines A-D from the endophytic fungus Colletotrichum salsolae SCSIO 41021 isolated from the mangrove Kandelia candel. Phytochemistry, 2020, 171.
5. Bin Yang; Huaming Tao; Xiuping Lin; Junfeng Wang; Shengrong Liao; Junde Dong; Xuefeng Zhou; Yonghong Liu, Prenylated indole alkaloids and chromone derivatives from the fungus Penicillium sp. SCSIO041218. Tetrahedron, 2018, 74, 77-82.
授权发明专利:
1. 环脯氨酸-亮氨酸在海洋污损生物防除中的应用.专利号: ZL200910213704.6
2. 环脯氨酸-2-N-羟基-异亮氨酸在海洋污损生物防除中的应用. 专利号:ZL200910213705.0
3. 一种深海海旋菌及其应用. 专利号:ZL200910192643.X
4. 吡啶酮生物碱类化合物及其制备方法和在制备抗肿瘤药物中的应用。专利号:ZL201410021280.4.
5. 生物碱类化合物在制抗肠道病毒及乙酰胆碱酯酶抑制剂药物中的应用。专利号:ZL201410021315.4.
参编专著:
1. Bin Yang, Xiuping Lin, Xuefeng Zhou, Xianwen Yang, and Yonghong Liu. Chemical and Biological Aspects of Marine Cosmeceuticals. Marine Cosmeceuticals Trends and Prospects. ISBN: 9781439860281, CRC Press, 2011. P11–38.
2. Bin Yang, Juan Liu, Junfeng Wang, Shengrong Liao and Yonghong Liu. Cytotoxic Cembrane Diterpenoids. Handbook of Anticancer Drugs from Marine Origin. ISBN: 978-3-319-07144-2, Springer publishers, 2015. P649-672.
3. Jing Hu, Bin Yang, Xiuping Lin, XueFeng Zhou, XianWen Yang, and Yonghong Liu. Bioactive metabolites from seaweeds. Handbook of Marine Macroalgae: Biotechnology and Applied Phycology. Online ISBN: 9781119977087, Wiley-Blackwell publisher, 2011. P262–284.