近期的研究工作主要有以下两方面：1. 利用组合生物合成技术对非达霉素进行结构多样化改造，期望发现新的抗菌活性更好的抗生素先导化合物，未来可用于治疗耐药型艰难梭菌感染类疾病。关于非达霉素碘化新机制方面的论文发表于I区SCI期刊Science China Chemistry,2021,64:1736-1742.,本人为该论文第一作者并申请了相关专利一项。2. 从海洋来源的微生物中发现具有生物活性的新型天然产物。含有硫元素的稠环生物碱在自然界相当罕见，从海绵共附生放线菌中发现两个硫代生物碱类化合物dassonmycins A和B，具有罕见的6/6/6/6多环稠合萘醌[2,3-e]哌嗪[1,2-c]硫代吗啉新骨架。上述研究成果以前封面文章的形式发表于I区SCI期刊Organic Letters，2021, 23 (8): 2858–2862），本人为共同通讯作者并获得授权专利一项。

2007/09–2010/06：中国科学院大学（中国科学院昆明植物研究所），药物化学专业博士;

2004/09–2007/06：河南大学药学院，生药学专业硕士;

1999/09–2002/06：河南大学药学院，药学专业专科毕业。

2012/12–今：中国科学院南海海洋研究所，副研究员；

2010/07–2012/11：中国科学院南海海洋研究所，助理研究员；

1.近五年发表文章20篇，授权专利8件。

2.代表性论文（第一作者/通讯作者）：

1） Haibo Zhang, Liping Zhang, Imran Khan, Guangtao Zhang, Yiguang Zhu & Changsheng Zhang.* A simple and facile iodination method of didechlorotiacumicin B and aromatic compounds. SCIENCE CHINA Chemistry, 2021,64:1736-1742.

2）Ruidong Chen (共同第一)，Haibo Zhang (共同第一), Gaiyun Zhang, Sumei Li，Guangtao Zhang, Yiguang Zhu，Jinsong Liu, Changsheng Zhang*，Characterizing Amosamine Biosynthesis in Amicetin Reveals AmiG as a Reversible Retaining lycosyltransferase，Journal of the American Chemical Society, 2013, 135(33):12152~12155.

3）Xinya Zhang,# Siqiang Chen,# Liping Zhang, Qingbo Zhang, Wenjun Zhang, Yuchan Chen, Weimin Zhang, Haibo Zhang,* and Changsheng Zhang.* Dassonmycins A and B, Polycyclic thioalkaloids from a marine sponge-derived Nocardiopsis dassonvillei SCSIO 40065. Organic Letters, 2021, 23 (8): 2858–2862. ( Front Cover paper )

4）Haibo Zhang, Xiaoxing Tian, Xiaohui Pu, Qingbo Zhang, Wenjun Zhang, and Changsheng Zhang*, Tiacumicin Congeners with Improved Antibacterial Activity from a Halogenase-Inactivated Mutant，Journal of Natural Products，2018, 81: 1219-1224.

5）Haibo Zhang,# Kumar Saurav,# Ziquan Yu, Attila Mándi, Tibor Kurtán, Jie Li, Xinpeng Tian, Qingbo Zhang, Wenjun Zhang, Changsheng Zhang*. α-Pyrones with diverse hydroxy substitutions from three marine-derived Nocardiopsis strains. Journal of Natural Products, 2016, 79(6): 1610–1618.

6）Haibo Zhang, JianXin Pu*, Yong Zhao, Fei He, Xiaonian Li, Xiao Luo, Liguang Lou, Handong Sun*, Bisleuconins A-D: A Pair of Epimeric ent-Kauranoid Dimers and Two New Asymmetric Analogues Isolated from Isodon leucophyllus, Tetrahedron Letters, 2011，52：6061–6066.

7）Haibo Zhang,Xue Du, Jianxin Pu*,Yuanyuan Wang,Fei He,Yong Zhao, Xiaonian Li, Xiao Luo,Weilie Xiao,Yan Li,Handong Sun*. Two novel diterpenoids from Isodon rubescens var. lushanensis. Tetrahedron Letters, 2010, 51(32): 4225-4228,

8）Imran Khan, Haibo Zhang,* Wei Liu, Liping Zhang, Fang Peng, Yuchan Chen, Qingbo Zhang, Guangtao Zhang, Weimin Zhang, and Changsheng Zhang.* Identification and bioactivity evaluation of secondary metabolites from Antarctic-derived Penicillium chrysogenum CCTCC M 2020019. RSC Advances, 2020, 10 (35): 20738-20744.

2013年获云南省自然科学一等奖（排名第9）